An MMSIG, for removing duplication protection for a multimedia messaging service interworking forwarding message, the MMSIG being respectively used as an originator or a receiver, connecting to an MMSC, and being set as follows:when the MMSIG is used as an originator, the original MMSIG sets the status of a request signaling and sends information to an opposite MMSIG used as a receiver, wherein the information is a forwarding message request; thus the recipient MMSIG determines a transmission type of the link of the MMSIG according to a setting status of the request signaling of the MMSIG, and determines whether the information is successfully received according to a status-identification code fed back by the request signaling or a response signaling, if successfully received, the normally received information will be delivered to the MMSC; andwhen the MMSIG is used as a receiver, the recipient MMSIG receives the information sent by an opposite MMSIG used as an originator, determines the transmission type of the link of the original MMSIG according to the setting status of the request signaling of the original MMSIG, and determines whether the information is successfully received according to a status-identification code fed back by the request signaling or the response signaling, if successfully received, the normally received information will be delivered to the MMSC.