Pre-Grant Publication Number: 20110021564
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Prior Art (16)
Title Association between symptoms of attention-deficit/ hyperactivity disorder and bulimic behaviors in a
ISBN
Description
An case report on the association of ADHD symptoms and bulimic behaviors. 99 subjects participated in this study.
Title The British Journal of Psychiatry
ISBN
Description
A report on 8 patients diagnosed with bulimia nervosa, and were given methyl amphetamine or placebo to treat their symptoms. The methyl amphetamine proved to be useful to reduce the amount of food eaten, and self-induced vomiting.
Title Effectiveness of medications used to attenuate antipsychotic-related weight gain and metabolic abnor
Description
Discusses the methodology in which the drugs in question (amantadine, dextroamphetamine, d-fenfluramine, famotidine, fluoxetine) are all drivers towards weight loss when administered on a constant schedule over a medium-term regimen. Placebo tests concluded that weight loss was a directly correlated to the administered drugs, by way of systematic shifts in the way the subject views the necessity to eat.
Title Journal of Women's Health
ISBN
Description
A case report of 6 patients that had comorbid bulimia and ADHD and were treated with the medication, dextroamphetamine. The report shows that the medication was useful for all six patients, and decreased their desire to binge eat. All six patients stayed in a healthy weight range.
Title Treatment of binge-eating disorder with topiramate: a clinical case series.
Description
A clinical trial in which binge-eating was treated with topiramate. This is relevant since the patent lists topiramate as an active agent
Title Pharmacologic Treatment of Binge Eating Disorder
ISBN
Description
A review of a number of different drugs used to treat binge eating disorder, including desipramine,
fluvoxamine, fluoxetine, sertraline, citalopram, dexfenfluramine, sibutramine, and topiramate. Most of these drugs are listed as additional active agents in the claims of the patent.
Title Effect of Orlistat in Obese Patients with Binge Eating Disorder
ISBN
Description
A study on the treatment of binge eating disorder and obesity using orlistat. Orlistat is one of the active agents listed in the patent to be administered along with the amphetamine prodrug, methylphenidate prodrug, or methylphenidate analog in the treatment.
Title Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trial
ISBN
Description
A study on the treatment of binge eating disorder using zonisamide. Zonisamide is one of the active agents listed in the patent to be administered along with the amphetamine prodrug, methylphenidate prodrug, or methylphenidate analog in the treatment.
Title the amphetamine prodrug, methylphenidate prodrug, or methylphenidate analog
ISBN
Description
A study on the treatment of binge eating disorder and obesity using topiramate. Topiramate is one of the active agents listed in the patent to be administered along with the amphetamine prodrug, methylphenidate prodrug, or methylphenidate analog in the treatment.
Title Efficacy of Methylphenidate in Bulimia Nervosa Comorbid with Attention-Deficit Hyperactivity Disorde
ISBN Journal: Int J Eat Disord
Description
This case described the beneficial effect on the binge eating component of bulimia nervosa of methylphenidate, which was prescribed to treat comorbid attention-deficit/hyperactivity disorder. Possible mechanisms of action are discussed
Title Methylphenidate Treatment for Bulimia Nervosa Associated with a Cluster B Personality Disorder
Description
This talks about a treatment for bulimia nervosa, which is related to binge eating, except that in bulimia nervosa, binges are followed by purging. The authors of this page did 2 case studies prescribing methylphenidates to two women. Both patients responded to MPH, reporting significant reduction in binge and purge frequency and ADHD-like symptoms, as shown by the decrease in Conners scores.
Patent/Application # 6,323,236
Description
This is a patent that uses topiramate, a sulfamate derivatives to treat Impulse Control Disorders (ICD's), including Binge Eating Disorder. According to claims 8 and 15 of McElroy’s patent, a therapeutically effective amount of topiramate in conjunction with a psychostimulant, in which amphetamine and methylphenidate are both listed, can help treat Binge eating disorder.
Patent/Application # 7,105,486
Description
Patent for lisdexamfetamine dimesylate, which was orginally assigned to New River Pharmaceuticals Inc.(but is now owned by Shire who acquired New River Pharmaceticals).
Title Influence of Methylphenidate on Eating in Obese Men
ISBN
Description
This article describes how methylphenidate and its analogs, derivatives, and prodrugs can be used to treat obesity.
Title A Controlled Clinical Comparison of Benzphetamine and D-Amphetamine in the Management of Obesity
ISBN
Description
Benzphetamine (amphetamine prodrug and anorexic drug) has been used as a treatment for obesity since it was approved by the FDA in 1960. In a double blind study, it was found to that there were no differences in weight loss for patients receiving Benzphetamine and D-Amphetamine. Lisdexamphetamine is a D-Amphetamine derivative.
Title MedPage Today
Description
The reference discloses the efficacy of a claimed amphetamine substance for treating ADHD - which is mentioned in the subject patent app along with eating disorders. A complete medical journal article is cited for additional information.
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