Manufacturers have already deployed RFID technology in products that could be spoiled during transportation due to temperature extremes. If the temperature exceeds a certain threshold, a permanent electrical change occurs in the RFID-based label. In this paper, a mobile diagnosis system based on RFID for food safety is developed. The developed system consists of a mobile server and a remote server. In the mobile server, a PDA equipped with RFID CF Reader Card is used to acquire the food temperatures from RFID sensors. Moreover, the multi-sensor fusion algorithm is applied to integrate the sensor information.