Pre-Grant Publication Number: 20100311834
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Prior Art (5)
Title Purified Eicosapentaenoic Acid Reduces Small Dense LDL, Remnant Lipoprotein Particles, and C-Reactiv
ISBN
Description
Purified EPA was administered and lipoprotein profiles were measured. This study is the first to demonstrate that purified EPA reduces sdLDL, remnants, and CRP, thereby potentially leading to the reduction in development of atherosclerosis and CVD in the metabolic syndrome.
Title Addition of Omega-3 Fatty Acid to Maintenance Medication Treatment for Recurrent Unipolar Depressive
ISBN
Description
Teaches using EPA only as an adjunct treatment for depression.
Patent/Application # 5502077
Description
This Orange Book patent teaches a composition comprising at least 80% EPA and DHA. The prior art discussion refers to reports that EPA alone was not effective in reducing blood pressure.
Title Omega 3 Fish Oil: EPA v. DHA
Description
This on-line article comparies EPA and DHA and includes a paragraph specifically comparing them and referring to earlier research.
Title American Journal of Clinical Nutrition
ISBN
Description
This research concluded that EA and DHA have different clinical impact in various ways, including glycemic effect. EPA and DHA had similar (not identical) impact on lipids - suggesting some differentiation.
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