Pre-Grant Publication Number: 20100297246
Filing Date: September 05, 2008Priority Date: September 05, 2008
Inventors: Mervyn Neale Weitzmann, George Richard Beck, Jin-Kyu Lee
Assignee(s): Emory University
Current U.S. Classification: 424, 424/496000, 435, 435/375000
View Prior Art for Claim 00014
The method of Claim 13, wherein the silica-based nanoparticle inhibits osteoclast activity in the subject by inhibiting an increase in a population of osteoclasts; inhibiting the differentiation of cells of a population of monocyte-macrophage cells into preosteoclasts; inhibiting the fusion of preosteoclasts into osteoclasts; or a combination thereof.